Product overview:

CABLES1 mouse monoclonal antibody,clone LBI2A3

Field of research:

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Summary:

This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Alternative names:

CABL1; CABLES; HsT2563; IK3-1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

CABLES1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human CABLES1 (NP_612384) produced in E.coli.

Clone:

LBI2A3

Conjugation:

Unconjugated

Gene name:

Cdk5 and Abl enzyme substrate 1

Symbol:

CABLES1

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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