Product overview:

PYGM mouse monoclonal antibody,clone LBI3F9

Field of research:

Insulin signaling pathway, Starch and sucrose metabolism

Summary:

This gene encodes a muscle enzyme involved in glycogenolysis. Highly similar enzymes encoded by different genes are found in liver and brain. Mutations in this gene are associated with McArdle disease (myophosphorylase deficiency), a glycogen storage disease of muscle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

Alternative names:

glycogen; glycogen phosphorylase; glycogen storage disease type V; glycogen storage disease type V); McArdle syndrome; muscle; muscle (McArdle syndrome; myophosphorylase; phosphorylase

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PYGM

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 698-842 of human PYGM (NP_005600) produced in E.coli.

Clone:

LBI3F9

Conjugation:

Unconjugated

Gene name:

phosphorylase, glycogen, muscle

Symbol:

PYGM

Pathway:

Insulin signaling pathway, Starch and sucrose metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com