Product overview:

PLG mouse monoclonal antibody,clone LBI4F5

Field of research:

Complement and coagulation cascades, Neuroactive ligand-receptor interaction

Summary:

The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Alternative names:

DKFZp779M0222

Species reactivity:

Human

Host:

Mouse

Target:

PLG

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 301-586 of human PLG (NP_000292) produced in E.coli.

Clone:

LBI4F5

Conjugation:

Unconjugated

Gene name:

plasminogen

Symbol:

PLG

Pathway:

Complement and coagulation cascades, Neuroactive ligand-receptor interaction

Function:

Druggable Genome, Protease, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

IHC 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com