Product overview:

RUNX3 mouse monoclonal antibody,clone LBI2G1

Field of research:

Request info at info@sobekbio.com

Summary:

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

AML2; CBFA3; PEBP2aC

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

RUNX3

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human RUNX3 (NP_001026850) produced in E.coli.

Clone:

LBI2G1

Conjugation:

Unconjugated

Gene name:

runt related transcription factor 3

Symbol:

RUNX3

Pathway:

Request info at info@sobekbio.com

Function:

Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com