Product overview:

LZTS1 mouse monoclonal antibody,clone LBI3D12

Field of research:

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Summary:

This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer. [provided by RefSeq, Nov 2009]

Alternative names:

F37; FEZ1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

LZTS1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human LZTS1 (NP_066300) produced in HEK293T Cell.

Clone:

LBI3D12

Conjugation:

Unconjugated

Gene name:

leucine zipper, putative tumor suppressor 1

Symbol:

LZTS1

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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