Product overview:

UHRF2 mouse monoclonal antibody,clone LBI4E10

Field of research:

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Summary:

This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012]

Alternative names:

NIRF; RNF107; TDRD23; URF2

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

UHRF2

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-288 of human UHRF2(NP_690856) produced in E.coli.

Clone:

LBI4E10

Conjugation:

Unconjugated

Gene name:

ubiquitin like with PHD and ring finger domains 2

Symbol:

UHRF2

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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