Product overview:

TLR8 mouse monoclonal antibody,clone LBI3A6

Field of research:

Toll-like receptor signaling pathway

Summary:

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008]

Alternative names:

CD288

Species reactivity:

Human

Host:

Mouse

Target:

TLR8

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 32-153 of human TLR8(NP_619542) produced in E.coli.

Clone:

LBI3A6

Conjugation:

Unconjugated

Gene name:

toll like receptor 8

Symbol:

TLR8

Pathway:

Toll-like receptor signaling pathway

Function:

Druggable Genome, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com