Product overview:

NMI mouse monoclonal antibody,clone LBI1A8

Field of research:

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Summary:

NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008]

Alternative names:

N-myc (and STAT) interactor; N-myc-interactor; N-myc and STAT interactor; N-myc interactor

Species reactivity:

Human

Host:

Mouse

Target:

NMI

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-223 of human NMI(NP_004679) produced in E.coli.

Clone:

LBI1A8

Conjugation:

Unconjugated

Gene name:

N-myc and STAT interactor

Symbol:

NMI

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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