Product overview:

CRY1 mouse monoclonal antibody,clone LBI6C6

Field of research:

Circadian rhythm - mammal

Summary:

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]

Alternative names:

PHLL1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

CRY1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 502-584 of human CRY1(NP_004066) produced in E.coli.

Clone:

LBI6C6

Conjugation:

Unconjugated

Gene name:

cryptochrome circadian clock 1

Symbol:

CRY1

Pathway:

Circadian rhythm - mammal

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com