Product overview:

TOP1 mouse monoclonal antibody,clone LBI3B9

Field of research:

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Summary:

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008]

Alternative names:

TOPI

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

TOP1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 93-151 of human TOP1(NP_003277) produced in E.coli.

Clone:

LBI3B9

Conjugation:

Unconjugated

Gene name:

topoisomerase (DNA) I

Symbol:

TOP1

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IHC 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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