Product overview:

PRMT7 mouse monoclonal antibody,clone LBI10A8

Field of research:

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Summary:

Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing (Miranda et al., 2004 [PubMed 15044439]). [supplied by OMIM, Mar 2008]. Transcript Variant: This variant (2) lacks an exon in the 5' UTR and in the 5' coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK304605.1 [ECO:0000332] RNAseq introns :: single sample supports all introns ERS025087, ERS025093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

Alternative names:

FLJ10640; KIAA1933

Species reactivity:

Human, Mouse

Host:

Mouse

Target:

PRMT7

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human PRMT7 (NP_061896) produced in HEK293T cell.

Clone:

LBI10A8

Conjugation:

Unconjugated

Gene name:

protein arginine methyltransferase 7

Symbol:

PRMT7

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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