Product overview:

PCMT1 mouse monoclonal antibody,clone LBI2E7

Field of research:

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Summary:

This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Alternative names:

PIMT

Species reactivity:

Human

Host:

Mouse

Target:

PCMT1

Isotype:

IgG2a

Immunogen:

Human recombinant protein fragment corresponding to amino acids 60-285 of human PCMT1(NP_005380) produced in E.coli.

Clone:

LBI2E7

Conjugation:

Unconjugated

Gene name:

protein-L-isoaspartate (D-aspartate) O-methyltransferase

Symbol:

PCMT1

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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