Product overview:

IQGAP1 mouse monoclonal antibody,clone LBI6E10

Field of research:

Adherens junction, Regulation of actin cytoskeleton

Summary:

This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008]

Alternative names:

HUMORFA01; p195; SAR1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

IQGAP1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 464-609 of human IQGAP1(NP_003861) produced in E.coli.

Clone:

LBI6E10

Conjugation:

Unconjugated

Gene name:

IQ motif containing GTPase activating protein 1

Symbol:

IQGAP1

Pathway:

Adherens junction, Regulation of actin cytoskeleton

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000, IHC 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com