Product overview:

WDR77 mouse monoclonal antibody,clone LBI5E9

Field of research:

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Summary:

WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]). [supplied by OMIM, Mar 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC016946.1, BC001679.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support ERS025081, ERS025082 [ECO:0000350] ##Evidence-Data-END##

Alternative names:

HKMT1069; MEP-50; MEP50; Nbla10071; p44; p44/Mep50

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

WDR77

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-250 of human WDR77 (NP_077007) produced in E.coli.

Clone:

LBI5E9

Conjugation:

Unconjugated

Gene name:

WD repeat domain 77

Symbol:

WDR77

Pathway:

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Function:

Stem cell - Pluripotency

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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