Product overview:

RORC mouse monoclonal antibody,clone LBI1G3

Field of research:

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Summary:

The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

NR1F3; RORG; RZR-GAMMA; RZRG; TOR

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

RORC

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-266 of human RORC (NP_005051) produced in E.coli.

Clone:

LBI1G3

Conjugation:

Unconjugated

Gene name:

RAR related orphan receptor C

Symbol:

RORC

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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