Product overview:

MYOT mouse monoclonal antibody,clone LBI5E11

Field of research:

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Summary:

This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2008]

Alternative names:

LGMD1; LGMD1A; MFM3; TTID; TTOD

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

MYOT

Isotype:

IgG1

Immunogen:

Full length human recombiant protein of human MYOT (NP_006781) produced in E.coli.

Clone:

LBI5E11

Conjugation:

Unconjugated

Gene name:

myotilin

Symbol:

MYOT

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:1000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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