Product overview:

TRMT12 mouse monoclonal antibody,clone LBI8C7

Field of research:

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Summary:

Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006). [supplied by OMIM, Mar 2008]. COMPLETENESS: complete on the 3' end.

Alternative names:

TRM12; TYW2

Species reactivity:

Human

Host:

Mouse

Target:

TRMT12

Isotype:

IgG2a

Immunogen:

Full length human recombinant protein of human TRMT12 (NP_060426) produced in E.coli.

Clone:

LBI8C7

Conjugation:

Unconjugated

Gene name:

tRNA methyltransferase 12 homolog

Symbol:

TRMT12

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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