Product overview:

RAB23 mouse monoclonal antibody,clone LBI1A3

Field of research:

Hedgehog signaling pathway

Summary:

This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Alternative names:

HSPC137

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

RAB23

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-234 of human RAB23(NP_899050) produced in E.coli.

Clone:

LBI1A3

Conjugation:

Unconjugated

Gene name:

RAB23, member RAS oncogene family

Symbol:

RAB23

Pathway:

Hedgehog signaling pathway

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com