Product overview:

CACNB1 mouse monoclonal antibody,clone LBI3H6

Field of research:

Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway

Summary:

The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

Alternative names:

CAB1; CACNLB1; CCHLB1

Species reactivity:

Human, Mouse

Host:

Mouse

Target:

CACNB1

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 1-269 of human CACNB1(NP_954855) produced in E.coli.

Clone:

LBI3H6

Conjugation:

Unconjugated

Gene name:

calcium voltage-gated channel auxiliary subunit beta 1

Symbol:

CACNB1

Pathway:

Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway

Function:

Druggable Genome, Ion Channels: Other

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500~2000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com