Product overview:

TGFBR3 mouse monoclonal antibody,clone LBI6B2

Field of research:

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Summary:

This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2010]

Alternative names:

betaglycan; BGCAN

Species reactivity:

Human

Host:

Mouse

Target:

TGFBR3

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 531-777 of human TGFBR3(NP_003234) produced in E.coli.

Clone:

LBI6B2

Conjugation:

Unconjugated

Gene name:

transforming growth factor beta receptor 3

Symbol:

TGFBR3

Pathway:

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Function:

Druggable Genome, Secreted Protein, Transmembrane

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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