Product overview:

CEACAM6 mouse monoclonal antibody,clone LBI5A10

Field of research:

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Summary:

This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]

Alternative names:

CD66c; CEAL; NCA

Species reactivity:

Human

Host:

Mouse

Target:

CEACAM6

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 35-257 of human CEACAM6(NP_002474) produced in E.coli.

Clone:

LBI5A10

Conjugation:

Unconjugated

Gene name:

carcinoembryonic antigen related cell adhesion molecule 6

Symbol:

CEACAM6

Pathway:

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Function:

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Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

IHC 1:150

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

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