Product overview:

TGM2 mouse monoclonal antibody,clone LBI4H5

Field of research:

Huntington's disease

Summary:

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Alternative names:

G-ALPHA-h; GNAH; HEL-S-45; TG2; TGC

Species reactivity:

Human

Host:

Mouse

Target:

TGM2

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human TGM2 (NP_004604) produced in HEK293T cell.

Clone:

LBI4H5

Conjugation:

Unconjugated

Gene name:

transglutaminase 2

Symbol:

TGM2

Pathway:

Huntington's disease

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:500, IHC 1:1000

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com