Product overview:

MAPT mouse monoclonal antibody,clone LBI6G3

Field of research:

Alzheimer's disease, MAPK signaling pathway

Summary:

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]

Alternative names:

DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; tau-40

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

MAPT

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 623-758 of human MAPT(NP_058519) produced in E.coli.

Clone:

LBI6G3

Conjugation:

Unconjugated

Gene name:

microtubule associated protein tau

Symbol:

MAPT

Pathway:

Alzheimer's disease, MAPK signaling pathway

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

1 mg/ml

Form:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Applications & dilution:

WB 1:2000, IHC 1:500

Storage buffer:

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage:

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com