Product overview:

Carrier-free (BSA/glycerol-free) UNG mouse monoclonal antibody, clone LBI1A11

Field of research:

Base excision repair, Primary immunodeficiency

Summary:

This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq]

Alternative names:

DGU; HIGM4; HIGM5; UDG; UNG1; UNG2; UNG15

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

UNG

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human UNG(NP_550433) produced in HEK293T cell.

Clone:

LBI1A11

Conjugation:

Unconjugated

Gene name:

Homo sapiens uracil DNA glycosylase (UNG), transcript variant 2, mRNA.

Symbol:

UNG

Pathway:

Base excision repair, Primary immunodeficiency

Function:

Druggable Genome, Stem cell - Pluripotency

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:150, IF 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com