Product overview:

Carrier-free (BSA/glycerol-free) LGALS3BP mouse monoclonal antibody, clone LBI1C2

Field of research:

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Summary:

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]

Alternative names:

90K; BTBD17B; CyCAP; gp90; M2BP; MAC-2-BP; TANGO10B

Species reactivity:

Human

Host:

Mouse

Target:

LGALS3BP

Isotype:

IgG1

Immunogen:

Human recombinant protein fragment corresponding to amino acids 19-300 of human LGALS3BP(NP_005558) produced in E.coli.

Clone:

LBI1C2

Conjugation:

Unconjugated

Gene name:

Homo sapiens galectin 3 binding protein (LGALS3BP), mRNA.

Symbol:

LGALS3BP

Pathway:

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Function:

Druggable Genome, Secreted Protein

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IF 1:100, FLOW 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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