Product overview:

Carrier-free (BSA/glycerol-free) PDE1B mouse monoclonal antibody, clone LBI6E4

Field of research:

Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism

Summary:

Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]). [supplied by OMIM]

Alternative names:

PDE1B1; PDES1B

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PDE1B

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human PDE1B(NP_000915) produced in HEK293T cell.

Clone:

LBI6E4

Conjugation:

Unconjugated

Gene name:

Homo sapiens phosphodiesterase 1B (PDE1B), transcript variant 1, mRNA.

Symbol:

PDE1B

Pathway:

Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com