Product overview:

Carrier-free (BSA/glycerol-free) PRKAR1B mouse monoclonal antibody, clone LBI9C5

Field of research:

Apoptosis, Insulin signaling pathway

Summary:

Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP. [supplied by OMIM]

Alternative names:

PRKAR1

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PRKAR1B

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human PRKAR1B (NP_002726) produced in HEK293T cell.

Clone:

LBI9C5

Conjugation:

Unconjugated

Gene name:

Homo sapiens protein kinase cAMP-dependent type I regulatory subunit beta (PRKAR1B), transcript variant 2, mRNA.

Symbol:

PRKAR1B

Pathway:

Apoptosis, Insulin signaling pathway

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IF 1:100, FLOW 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com