Product overview:

Carrier-free (BSA/glycerol-free) DCK mouse monoclonal antibody, clone LBI16G6

Field of research:

Purine metabolism, Pyrimidine metabolism

Summary:

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008]

Alternative names:

MGC117410; MGC138632

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

DCK

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human DCK (NP_000779) produced in HEK293T cell.

Clone:

LBI16G6

Conjugation:

Unconjugated

Gene name:

Homo sapiens deoxycytidine kinase (DCK), mRNA.

Symbol:

DCK

Pathway:

Purine metabolism, Pyrimidine metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:500~2000, IHC 1:150, FLOW 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com