Product overview:

Carrier-free (BSA/glycerol-free) HDAC6 mouse monoclonal antibody, clone LBI4C5

Field of research:

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Summary:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq]

Alternative names:

CPBHM; HD6; JM21; PPP1R90

Species reactivity:

Human, Monkey, Rat, Dog

Host:

Mouse

Target:

HDAC6

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human HDAC6 (NP_006035) produced in HEK293T cell.

Clone:

LBI4C5

Conjugation:

Unconjugated

Gene name:

Homo sapiens histone deacetylase 6 (HDAC6), transcript variant 5, mRNA.

Symbol:

HDAC6

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:1000~2000, IF 1:100, FLOW 1:100, IHC 1:150

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com