Product overview:

Carrier-free (BSA/glycerol-free) KEAP1 mouse monoclonal antibody, clone LBI1G2

Field of research:

Ubiquitin mediated proteolysis

Summary:

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq]

Alternative names:

INrf2; KLHL19

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

KEAP1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human KEAP1 (NP_987096) produced in HEK293T cell.

Clone:

LBI1G2

Conjugation:

Unconjugated

Gene name:

Homo sapiens kelch like ECH associated protein 1 (KEAP1), transcript variant 1, mRNA.

Symbol:

KEAP1

Pathway:

Ubiquitin mediated proteolysis

Function:

Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IF 1:100, FLOW 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com