Product overview:

Carrier-free (BSA/glycerol-free) PDE4A mouse monoclonal antibody, clone LBI1F5

Field of research:

Progesterone-mediated oocyte maturation, Purine metabolism

Summary:

Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. PDE4A is a class IV cAMP-specific PDE

Alternative names:

DPDE2; PDE4; PDE46

Species reactivity:

Human, Rat

Host:

Mouse

Target:

PDE4A

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human PDE4A (NP_006193) produced in HEK293T cell.

Clone:

LBI1F5

Conjugation:

Unconjugated

Gene name:

Homo sapiens phosphodiesterase 4A (PDE4A), transcript variant 4, mRNA.

Symbol:

PDE4A

Pathway:

Progesterone-mediated oocyte maturation, Purine metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:50, IF 1:100, FLOW 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com