Product overview:

Carrier-free (BSA/glycerol-free) RALBP1 mouse monoclonal antibody, clone LBI11B2

Field of research:

Pancreatic cancer, Pathways in cancer

Summary:

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin

Alternative names:

RIP1; RLIP1; RLIP76

Species reactivity:

Human, Mouse, Rat, Dog

Host:

Mouse

Target:

RALBP1

Isotype:

IgG1

Immunogen:

Full length human recombinant protein of human RALBP1 (NP_006779) produced in HEK293T cell.

Clone:

LBI11B2

Conjugation:

Unconjugated

Gene name:

Homo sapiens ralA binding protein 1 (RALBP1), mRNA.

Symbol:

RALBP1

Pathway:

Pancreatic cancer, Pathways in cancer

Function:

Request info at info@sobekbio.com

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IF 1:100, Flow 1:100, IP: 4ug/mL

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com