Product overview:

Carrier-free (BSA/glycerol-free) FKBP5 mouse monoclonal antibody, clone LBI3E9

Field of research:

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Summary:

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition.It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Alternative names:

AIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

FKBP5

Isotype:

IgG1

Immunogen:

Full-length protein expressed in 293T cell transfected with human FKBP5 expression vector

Clone:

LBI3E9

Conjugation:

Unconjugated

Gene name:

Homo sapiens FKBP prolyl isomerase 5 (FKBP5), transcript variant 1, mRNA.

Symbol:

FKBP5

Pathway:

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Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:50, IF 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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