Product overview:

Carrier-free (BSA/glycerol-free) PDE10A mouse monoclonal antibody, clone LBI3G9

Field of research:

Progesterone-mediated oocyte maturation, Purine metabolism

Summary:

Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate (Fujishige et al., 2000 [PubMed 10998054]). [supplied by OMIM]

Alternative names:

FLJ11894; FLJ25677; HSPDE10A

Species reactivity:

Human, Mouse, Rat

Host:

Mouse

Target:

PDE10A

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human PDE10A (NP_006652) produced in HEK293T cell.

Clone:

LBI3G9

Conjugation:

Unconjugated

Gene name:

Homo sapiens phosphodiesterase 10A (PDE10A), transcript variant 2, mRNA.

Symbol:

PDE10A

Pathway:

Progesterone-mediated oocyte maturation, Purine metabolism

Function:

Druggable Genome

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

IF 1:100, FLOW 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com