Product overview:

Carrier-free (BSA/glycerol-free) KDM4C mouse monoclonal antibody, clone LBI5B9

Field of research:

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Summary:

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

Alternative names:

GASC1; JHDM3C; JMJD2C; TDRD14C

Species reactivity:

Human, Rat

Host:

Mouse

Target:

KDM4C

Isotype:

IgG1

Immunogen:

Full-length protein expressed in 293T cell transfected with human KDM4C expression vector

Clone:

LBI5B9

Conjugation:

Unconjugated

Gene name:

Homo sapiens lysine demethylase 4C (KDM4C), transcript variant 1, mRNA.

Symbol:

KDM4C

Pathway:

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Function:

Druggable Genome, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:2000, IHC 1:50, IF 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com