Product overview:

Carrier-free (BSA/glycerol-free) BUB1B mouse monoclonal antibody, clone LBI11D7

Field of research:

Cell cycle

Summary:

This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome(APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

Alternative names:

Bub1A; BUB1beta; BUBR1; hBUBR1; MAD3L; MVA1; SSK1

Species reactivity:

Human, Monkey

Host:

Mouse

Target:

BUB1B

Isotype:

IgG1

Immunogen:

Full-length protein expressed in 293T cell transfected with human BUB1B expression vector

Clone:

LBI11D7

Conjugation:

Unconjugated

Gene name:

Homo sapiens BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B), mRNA.

Symbol:

BUB1B

Pathway:

Cell cycle

Function:

Druggable Genome, Protein Kinase, Stem cell - Pluripotency

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:1000 IHC 1:50 IF 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com