Product overview:

Carrier-free (BSA/glycerol-free) TRIB2 mouse monoclonal antibody, clone LBI8D11

Field of research:

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Summary:

This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.

Alternative names:

C5FW; GS3955; TRB2

Species reactivity:

Human, Mouse

Host:

Mouse

Target:

TRIB2

Isotype:

IgG2b

Immunogen:

Full length human recombinant protein of human TRIB2 (NP_067675) produced in HEK293T cell.

Clone:

LBI8D11

Conjugation:

Unconjugated

Gene name:

Homo sapiens tribbles pseudokinase 2 (TRIB2), transcript variant 1, mRNA.

Symbol:

TRIB2

Pathway:

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Function:

Druggable Genome, Protein Kinase

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:1000~2000, IHC 1:50, IF 1:50, FLOW 1:100

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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