Product overview:

Carrier-free (BSA/glycerol-free) SSB mouse monoclonal antibody, clone LBI3H9

Field of research:

Systemic lupus erythematosus

Summary:

La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(H) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAsassociated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus

Alternative names:

La; La/SSB; LARP3

Species reactivity:

Human, Dog

Host:

Mouse

Target:

SSB

Isotype:

IgG2a

Immunogen:

Full-length protein expressed in 293T cell transfected with human SSB expression vector

Clone:

LBI3H9

Conjugation:

Unconjugated

Gene name:

Homo sapiens small RNA binding exonuclease protection factor La (SSB), transcript variant 1, mRNA.

Symbol:

SSB

Pathway:

Systemic lupus erythematosus

Function:

Stem cell - Pluripotency, Transcription Factors

Purification:

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Concentration:

Form:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Applications & dilution:

WB 1:1000~2000, IHC 1:150, IF 1:100, FLOW 1:100, IP 2ug/500ul

Storage buffer:

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Storage:

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com