Background:

CCL20, also known as macrophage infiltrating factor protein 3α, is a C-C chemokine that specifically binds to the receptor CCR6. CCL20 is produced in various tissues and by a wide range of immune cells, including neutrophils, natural killer cells, T-helper type 17(Th17) cells, B cells, and various antigen-presenting cells, such as dendritic cells(DCs), Langerhans cells, and macrophages. Increased expression of CCL20 is likely involved in the increased recruitment of dendritic cells observed in fibroinflammatory diseases such as chronic obstructive pulmonary disease(COPD). CCL20 expression is increased by the proinflammatory cytokine IL-1 beta.

Clonality:

polyclonal

Classification:

Primary antibody

Alternative names:

Beta chemokine exodus 1, C C motif chemokine 20, CC chemokine LARC, CCL20, CKb4, LARC, MIP 3 alpha, MIP 3a, MIP3A, MIP-3α, SCYA20, Small inducible cytokine A20, ST38

Specificity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

chemokine(C-C motif) ligand 20

Purification:

Immunogen affinity purified

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

11kd

Form:

liquid

Applications:

ELISA, IHC

Recommended dilution:

IHC: 1:50-1:500

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

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