Background:

Putative ATP-dependent protease which plays a role in mitochondrial protein metabolism. Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. Requires to control the accumulation of nonassembled respiratory chain subunits(NDUFB6, OX4 and ND1). Seems to act in the processing of OPA1.

Clonality:

polyclonal

Classification:

Primary antibody

Alternative names:

FTSH, FTSH1, Meg 4, MEG4, PAMP, YME1 like 1(S. cerevisiae), YME1 like protein 1, YME1L, YME1L1

Specificity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

YME1-like 1(S. cerevisiae)

Purification:

Immunogen affinity purified

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

86 kDa, Observed 86 kDa, 60 kDa

Form:

liquid

Applications:

ELISA, WB, IHC, IF

Recommended dilution:

WB: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:50-1:200

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

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