anti- XRN1 antibody
Background:
Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA(By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma(OGS).
Clonality:
polyclonal
Classification:
Primary antibody
Alternative names:
5 3 exoribonuclease 1, 5' 3' exoribonuclease 1, DKFZp434P0721, DKFZp686B22225, DKFZp686F19113, FLJ41903, SEP1, XRN1
Specificity:
Human, Mouse
Host:
Rabbit
Isotype:
IgG
Immunogen:
5'-3' exoribonuclease 1
Purification:
Immunogen affinity purified
Purity:
≥95% as determined by SDS-PAGE
Calculated molecular weight:
192 kDa
Form:
liquid
Applications:
ELISA, WB, IHC, IF
Recommended dilution:
WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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