Background:

Involved in the endosomal multivesicular bodies(MVB) pathway. MVBs contain intraluminal vesicles(ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR(By similarity). Involved in HIV-1 budding.

Clonality:

polyclonal

Classification:

Primary antibody

Alternative names:

C6orf55, DRG 1, DRG1, FLJ27228, HSPC228, LIP5, LYST interacting protein 5, My012, SBP1, SKD1 binding protein 1, VTA1

Specificity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Vps20-associated 1 homolog(S. cerevisiae)

Purification:

Immunogen affinity purified

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

42 kDa

Form:

liquid

Applications:

ELISA, WB, IF

Recommended dilution:

WB: 1:1000-1:10000；IF: 1:10-1:100

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

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