anti- TNFAIP1 antibody
Background:
Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
Clonality:
monoclonal
Classification:
Primary antibody
Alternative names:
BACURD2, EDP1
Specificity:
Human
Host:
Mouse
Isotype:
IgG1
Immunogen:
tumor necrosis factor, alpha-induced protein 1(endothelial)
Purification:
Protein A+G purification
Purity:
≥95% as determined by SDS-PAGE
Calculated molecular weight:
Request info at info@sobekbio.com
Form:
liquid
Applications:
ELISA, WB, IHC
Recommended dilution:
Request info at info@sobekbio.com
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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