Background:

Transcription factor that specifically recognizes and binds E-box sequences(5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.

Clonality:

polyclonal

Classification:

Primary antibody

Alternative names:

bHLHe33, RCCP2, TFE3, TFEA, Transcription factor E3

Specificity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

transcription factor binding to IGHM enhancer 3

Purification:

Immunogen affinity purified

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

65KD

Form:

liquid

Applications:

ELISA, WB, IP,IHC

Recommended dilution:

WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:50-1:500

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

More info:

Email: info@sobekbio.com

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