anti- SNX17 antibody
Background:
Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate(PtdIns(3P)).
Clonality:
polyclonal
Classification:
Primary antibody
Alternative names:
KIAA0064
Specificity:
Human, Mouse, Rat
Host:
Rabbit
Isotype:
IgG
Immunogen:
sorting nexin 17
Purification:
Immunogen affinity purified
Purity:
≥95% as determined by SDS-PAGE
Calculated molecular weight:
Request info at info@sobekbio.com
Form:
liquid
Applications:
ELISA, WB, IF, IHC, IP
Recommended dilution:
Request info at info@sobekbio.com
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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