anti- NUP85 antibody
Background:
Essential component of the nuclear pore complex(NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade.
Clonality:
polyclonal
Classification:
Primary antibody
Alternative names:
NUP75, PCNT1
Specificity:
Human, Mouse
Host:
Rabbit
Isotype:
IgG
Immunogen:
nucleoporin 85kDa
Purification:
Immunogen affinity purified
Purity:
≥95% as determined by SDS-PAGE
Calculated molecular weight:
70-75kd
Form:
liquid
Applications:
ELISA, WB, IHC, IF
Recommended dilution:
Request info at info@sobekbio.com
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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