Background:

nNOS belongs to the NOS family. NOS1 produces nitric oxide(NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. NO is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. NO is synthesized from L-arginine by nitric oxide synthases. NOS1 is a nitric oxide synthase which is highly expressed in skeletal muscle. Genetic variations in NOS1 gene are associated with susceptibility to infantile hypertrophic pyloric stenosis type 1(IHPS1).The antibody can recognize isoform 1,2,4 of NOS1.

Clonality:

polyclonal

Classification:

Primary antibody

Alternative names:

bNOS, Constitutive NOS, IHPS1, N NOS, NC NOS, Neuronal NOS, Nitric oxide synthase, brain, nNOS, NOS, NOS type I, NOS1

Specificity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

nitric oxide synthase 1(neuronal)

Purification:

Immunogen affinity purified

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

161kd

Form:

liquid

Applications:

ELISA, IHC

Recommended dilution:

IHC: 1:20-1:200

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

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