anti- NCOA6 antibody
Background:
Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist-and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids(GR and ERs), retinoids(RARs and RXRs), thyroid hormone(TRs), vitamin D3(VDR) and prostanoids(PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.
Clonality:
polyclonal
Classification:
Primary antibody
Alternative names:
AIB3, KIAA0181, RAP250, TRBP
Specificity:
Human, Mouse
Host:
Rabbit
Isotype:
IgG
Immunogen:
nuclear receptor coactivator 6
Purification:
Immunogen affinity purified
Purity:
≥95% as determined by SDS-PAGE
Calculated molecular weight:
68 kDa ; 219 kDa ; 110 kDa
Form:
liquid
Applications:
ELISA, IP
Recommended dilution:
Request info at info@sobekbio.com
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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