anti- LRWD1 antibody
Background:
Required for G1/S transition. Recruits and stabilizes the origin recognition complex(ORC) onto chromatin during G1 to establish pre-replication complex(preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
Clonality:
polyclonal
Classification:
Primary antibody
Alternative names:
CENP-33, ORCA
Specificity:
Human
Host:
Rabbit
Isotype:
IgG
Immunogen:
leucine-rich repeats and WD repeat domain containing 1
Purification:
Immunogen affinity purified
Purity:
≥95% as determined by SDS-PAGE
Calculated molecular weight:
85 kDa
Form:
liquid
Applications:
ELISA, WB
Recommended dilution:
Request info at info@sobekbio.com
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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