Background:

This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms.

Clonality:

polyclonal

Classification:

Primary antibody

Alternative names:

EZF, GKLF, KLF4

Specificity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Kruppel-like factor 4 (gut)

Purification:

Immunogen affinity purified

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

50 kDa

Form:

liquid

Applications:

ELISA, WB

Recommended dilution:

WB: 1:200-1:2000

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

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